Isolation of lappaconitine from Aconitum septentrionale roots by adsorption

摘要

Extracts of Aconitum septentrionale Koelle roots obtained using chloroform, isopropanol, and ethanol were purified using chloroform and basic gamma-Al2O3. Ballast materials were selectively adsorbed by gamma-Al2O3, increasing the mass fraction of lappaconitine in the extract. The ethanol extract was purified most. The degree of lappaconitine extraction by chloroform was unaffected by the presence of gamma-Al2O3. However, the mass fraction in the extract and lappaconitine extraction from Aconitum septentrionale were increased more than twice.