Search for compounds with antiviral activity among synthetic (-)-cytisine derivatives

Tsypysheva I.P.; Kovalskaya A.V.; Lobov A.N.; Zarubaev V.V.; Karpinskaya L.A.; Petrenko I.A.; Nikolaeva E.A.; Shtro A.A.; Yunusov M.S.

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Search for compounds with antiviral activity among synthetic (-)-cytisine derivatives

机译：在合成（-）-胱氨酸衍生物中寻找具有抗病毒活性的化合物

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The antiviral activity of several amides and thio- and carboxamides of (-)-cytisine in addition to bromination and nitration products of its 2-pyridone core was studied. Compounds with a selectivity index close to 10 were found.

机译：除了（2-）-胱氨酸的2-吡啶酮核心的溴化和硝化产物外，还研究了（-）-胱氨酸的几种酰胺，硫代和羧酰胺的抗病毒活性。发现选择性指数接近10的化合物。

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来源
《Chemistry of Natural Compounds》 |2013年第6期|共5页
作者
Tsypysheva I.P.; Kovalskaya A.V.; Lobov A.N.; Zarubaev V.V.; Karpinskaya L.A.; Petrenko I.A.; Nikolaeva E.A.; Shtro A.A.; Yunusov M.S.;
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原文格式 PDF
正文语种 eng
中图分类化学;
关键词
(-)-cytisine; H1N1 flu virus;

机译：（-）-胱氨酸;H1N1流感病毒;

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1. Search for compounds with antiviral activity among synthetic (-)-cytisine derivatives [J] . Tsypysheva I.P., Kovalskaya A.V., Lobov A.N., Chemistry of Natural Compounds . 2013,第6期

机译：在合成（-）-胱氨酸衍生物中寻找具有抗病毒活性的化合物
2. Diels-Alder adducts of 3-N-substituted derivatives of (-)-Cytisine as influenza A/H1N1 virus inhibitors; stereodifferentiation of antiviral properties and preliminary assessment of action mechanism [J] . Tsypysheva Inna, Kovalskaya Alena, Petrova Polina, Tetrahedron . 2019,第21期

机译：（ - ） - 细胞素为甲型流感A / H1N1病毒抑制剂的二氧化物 - alder加合物; 抗病毒性质的立体化及作用机制的初步评估
3. Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives. [J] . Tonelli M, Simone M, Tasso B, Bioorganic and medicinal chemistry . 2010,第8期

机译：苯并咪唑衍生物的抗病毒活性。二。 2-苯基苯并咪唑衍生物的抗病毒活性。
4. IN SEARCH OF SYNTHETIC LOW-MOLECULAR PEPTIDE DERIVATIVES WITH ACTIVITY AGAINST FUNGAL PATHOGENS [C] . Regina Kasprzykowska, Franciszek Kasprzykowski, Anna Lesniewska the European Peptide Symposium . 2007

机译：寻找具有针对真菌病原体的活性的合成低分子肽衍生物
5. Identification and characterization of compounds with antiviral activity against influenza viruses. [D] . Vazquez, Ana Carolina. 2008

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7. A few atoms make the difference: Synthetic, CD, NMR and computational studies on antiviral and antibacterial activities of glycopeptide antibiotic aglycon derivatives [O] . Bereczki, Ilona, Mándi, Attila, Rőth, Erzsébet, 2017

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Search for compounds with antiviral activity among synthetic (-)-cytisine derivatives

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