Membrane-active properties of crambin

摘要

A thionin-like protein with M.M. 5 kDa has been isolated from Crambe kotschyana seeds. It has been shown that crambin possesses a low lytic action on erythrocytes but inhibits the Ca-ATPase of the sarcoplasmic reticulum of rabbit skeletal muscles. A disordering action of crambin on the structures of both the sarcoplasmic reticulum and liposomes has been established by ESR and microcalorimetry.