The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition

Hippolyte Loyse; Maillard Anne M.; Rodriguez-Herreros Borja; Pain Aurelie; Martin-Brevet Sandra; Ferrari Carina; Conus Philippe; Mace Aurelien; Hadjikhani Nouchine; Metspalu Andres; Reigo Anu; Kolk Anneli; Maennik Katrin; Barker Mandy; Isidor Bertrand; Le Caignec Cedric; Mignot Cyril; Schneider Laurence; Mottron Laurent; Keren Boris; David Albert; Doco-Fenzy Martine; Gerard Marion; Bernier Raphael; Goin-Kochel Robin P.; Hanson Ellen; Snyder LeeAnne Green; Ramus Franck; Beckmann Jacques S.; Draganski Bogdan; Reymond Alexandre; Jacquemont Sebastien

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The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition

机译：16p11.2位点的基因组拷贝数可调节语言，言语记忆和抑制

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BACKGROUND: Deletions and duplications of the 16p11.2 BP4-BP5 locus are prevalent copy number variations (CNVs), highly associated with autism spectrum disorder and schizophrenia. Beyond language and global cognition, neuropsychological assessments of these two CNVs have not yet been reported.

机译：背景：16p11.2 BP4-BP5基因座的缺失和重复是普遍存在的拷贝数变异（CNV），与自闭症谱系障碍和精神分裂症高度相关。除了语言和全球认知之外，尚未报道这两种CNV的神经心理学评估。

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《Biological psychiatry 》 |2016年第2期| 共11页
作者
Hippolyte Loyse; Maillard Anne M.; Rodriguez-Herreros Borja; Pain Aurelie; Martin-Brevet Sandra; Ferrari Carina; Conus Philippe; Mace Aurelien; Hadjikhani Nouchine; Metspalu Andres; Reigo Anu; Kolk Anneli; Maennik Katrin; Barker Mandy; Isidor Bertrand; Le Caignec Cedric; Mignot Cyril; Schneider Laurence; Mottron Laurent; Keren Boris; David Albert; Doco-Fenzy Martine; Gerard Marion; Bernier Raphael; Goin-Kochel Robin P.; Hanson Ellen; Snyder LeeAnne Green; Ramus Franck; Beckmann Jacques S.; Draganski Bogdan; Reymond Alexandre; Jacquemont Sebastien;
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正文语种 eng
中图分类神经病学与精神病学 ;
关键词
16p11.2; ASD; Copy number variation; Inhibition; Language; Memory;

机译：16p11.2;ASD;拷贝数变化;抑制;语言;记忆;

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1. The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition [J] . Hippolyte Loyse, Maillard Anne M., Rodriguez-Herreros Borja, Biological psychiatry . 2016 ,第2期

机译：16p11.2位点的基因组拷贝数可调节语言，言语记忆和抑制
2. Contributions of language and memory demands to verbal memory performance in language-learning disabilities. [J] . Isaki E, Spaulding TJ, Plante E Journal of communication disorders . 2008 ,第6期

机译：语言和记忆的要求对语言学习障碍者的言语记忆表现产生了影响。
3. The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity [J] . A M Maillard, A Ruef, F Pizzagalli, Molecular Psychiatry . 2015 ,第1期

机译：16p11.2基因座可调节自闭症，精神分裂症和肥胖症常见的大脑结构
4. The CineLingua Approach: Verbal and Non-verbal Features in Second Language Acquisition. Film Narrative to Anchor Comprehension and Production [C] . Rosa Volpe COST 2102 International Conference on Verbal and Nonverbal Features of Human-Human and Human-Machine Interaction . 2008

机译：Cinelingua方法：第二语言习得中的口头和非口头特征。电影叙事以锚定理解和生产
5. The effects of locus of control, working memory, motivation, and verbal ability on foreign language learning. [D] . Ebrahim, Saleh Ali. 1998

机译：控制源，工作记忆，动机和言语能力对外语学习的影响。
6. Training of verbal creativity modulates brain activity in regions associated with language‐ and memory‐related demands [O] . Andreas Fink, Mathias Benedek, Karl Koschutnig, 2015

机译：言语创造力的训练可调节与语言和记忆相关的需求相关区域的大脑活动
7. The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition. [O] . Hippolyte, L., Maillard, A.M., Rodriguez-Herreros, B., 2016

机译：16p11.2位点的基因组拷贝数可调节语言，语言记忆和抑制力。

The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition

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