Molecular epidemiology of Theileria orientalis in Australia and development of a molecular method for differentiation of T. orientalis genotypes

摘要

Bovine theileriosis caused by T. orientalis is prevalent throughout Japan, Korea and parts of Russia and China. The distribution of benign Theileria related to T. orientalis often referred to as T. buffeli appears to be worldwide, but is less frequently associated with clinical disease although some fatal cases have been reported to occur in America. Based on the major piroplasm surface protein (MPSP) gene, there are eight genetic types (genotypes) currently comprising the T. orientalis complex. These types include type1 (Chitose), type2 (Ikeda), type3 (Buffeli) and type-4-8 yet to be classified with taxonomically. Mixed infection with different types of T. orientalis in cattle are common in Japan, Korea, and China. Herein, I report the molecular epidemiology of T. orientalis in Australia and development of molecular diagnostic method for differentiation of T. orientalis genotypes.