An Efficient Method for the Preparation of Vicinal Tertiary Diamines by Reductive Coupling of Aminoacetals Mediated by Low Valent Titanium Iodide Species

摘要

Aminoacetals, easily prepared by condensation of aromatic aldehydes, secondary amines and alcohols, are reductively coupled by using low valent titanium iodide species to afford the corresponding coupling products, vicinal tertiary diamines, in good to high yields under mild reaction conditions.