Immunomodulating effect of dry powder of Ocimum sanctum and leaf gall of Ficus racemosa leaves in broilers naturally infected with IBD virus.

摘要

Fifty commercial broilers (6 weeks old), vaccinated with LaSota vaccine when 1 day old and having previously been exposed to a mild outbreak of infectious bursal disease (IBD), received the following treatments: untreated (control), revaccination at6 weeks, revaccination at 6 weeks + fed O. sanctum [O. tenuiflorum] leaf powder (2 g/kg feed) for 2 weeks, revaccination at 6 weeks + fed F. racemosa leaf gall extract (2 g/kg feed) for 2 weeks, or fed O. sanctum powder + F. racemosa extract for 2 weeks. Effects on the humoral immune response against Newcastle disease virus antigen and the cell-mediated immune response (DNCB contact skin sensitivity test) were evaluated. The plant preparations had a specific humoral immunostimulatory effect even in birds immunosuppressed due to IBD attack. The cellular reaction was intense in O. sanctum-treated birds and in those treated with both plant preparations.