Therapeutic efficacy of different drugs on gout in broilers.

摘要

The study was conducted to determine the therapeutic efficacy of different drugs against gout in broilers. 120 broilers, 2 weeks old, from a commercial broiler farm showing stunted growth, ruffled feathers, recumbency and laboured breathing, and confirmed visceral gout were included in the study. Groups I, II and III were treated with nephtone liquid, polyherbal drug, from M/S India Herbs at 16 ml/100 birds for 14 days, followed by 28 ml/100 birds for another 14 days in drinking water; Avisol powder from MIS Venky's India Ltd at 10 g/100 birds for 5 days; and 40 g molasses, 10 g skim milk powder/litre of drinking water with 4000 IU vitamin A/bird for 28 days, respectively. Groups IV and V served as affected and healthy controls. Blood samples were collected at day 0, followed by every 7 days interval up to full course treatment. Results revealed that the mean serum uric acid and creatinine levels significantly increased in all gout affected birds on day 0 of treatment when compared with healthy control. The serum uric acid and creatinine levels decreased in all treatment groups. However, the nephtone treated group had the most significant decrease in uric acid and creatinine levels, but still higher than the healthy control. The nephtone treated birds had significantly higher liveweight gain than the other groups. The mortality rates observed in groups I, II and III were 36.67, 50 and 53.33%, respectively. It is concluded that the treatment programmes have no significant effect in severely gout affected birds.