Two-Year Follow-Up of the MOSAIC Trial: A MultiCenter Randomized Controlled Trial Comparing Two Psychological Treatments in Adult Outpatients with Broadly Defined Anorexia Nervosa

摘要

Objective: This study reports follow-up data from a multicenter randomized controlled trial (n=142) comparing the Maudsley Model of Anorexia Nervosa Treatment for Adults (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients with broadly defined anorexia nervosa (AN). At 12 months postrandomization, all patients had statistically significant improvements in body mass index (BMI), eating disorder (ED) symptomatology and other outcomes with no differences between groups. MANTRA was more acceptable to patients. The present study assessed whether gains were maintained at 24 months postrandomization.