Multi-step Synthesis of a Protected Monosaccharide Unit by Iterative Reactions in Microreactors and Fluorous Liquid-phase Extractions

摘要

We describe a process that simultaneously achieves micro-reaction synthesis and fluorous liquid-phase extraction in a single system. Use of this method in multi-step synthesis of a protected monosaccharide unit yielded the desired product. Moreover, the total synthesis time, including an only single column chromatography as the last step, was significantly shortened compared with general synthetic methods.