首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Contemporary treatment strategy for spinal metastasis: the 'LMNOP' system.
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Contemporary treatment strategy for spinal metastasis: the 'LMNOP' system.

机译:脊柱转移的当代治疗策略:“ LMNOP”系统。

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The choice of treatment for spinal metastasis is complex because (1) it depends on several inter-related clinical and radiologic factors, and (2) a wide range of management options has evolved in recent years. While radiation therapy and surgery remain the cornerstones of treatment, radiosurgery and percutaneous vertebral augmentation have also established a role. Classification systems have been developed to aid in the decision-making process, and each has different strengths and weaknesses. The comprehensive scoring systems developed to date provide an estimate of life expectancy, but do not provide much advice on the choice of treatment. We propose a new decision model that describes the key factors in formulating the management plan, while recognizing that the care of each patient remains highly individualized. The system also incorporates the latest changes in technology. The LMNOP system evaluates the number of spinal Levels involved and the Location of disease in the spine (L), Mechanical instability (M), Neurology (N), Oncology (O), Patient fitness, Prognosis and response to Prior therapy (P).
机译:脊柱转移瘤的治疗选择很复杂,因为(1)它取决于几个相互关联的临床和放射学因素,并且(2)近年来已经发展了多种管理选择。尽管放射疗法和外科手术仍然是治疗的基石,但放射外科手术和经皮椎体隆突术也已经发挥了作用。已经开发了分类系统来辅助决策过程,每个分类系统都有各自的优缺点。迄今为止开发的综合评分系统提供了预期寿命的估计,但并未提供有关治疗选择的大量建议。我们提出了一个新的决策模型,该模型描述了制定管理计划的关键因素,同时认识到每个患者的护理仍然高度个人化。该系统还结合了最新的技术变化。 LMNOP系统评估涉及的脊柱水平数量以及脊椎疾病的位置(L),机械不稳定(M),神经病学(N),肿瘤学(O),患者适应性,预后和对先前治疗的反应(P) 。

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