Oligoarene Strategy for Catalyst Development.Hydroxylated Oligoarene-type Phosphines for Palladium-catalyzed Cross Coupling

摘要

Various oligoarene-type phosphines having a hydroxy group were synthesized based on a two-step repetitive method that we developed,and these phosphines were used as ligands for palladium in catalytic cross coupling with Grignard reagents.The study revealed that a hydroxylated terphenylphosphine accelerated the rate of the cross coupling of o-bromophenol and exhibited preference for the ortho-isomer over the meta-and para-iso-mers.