Preparation of Zinc-Homoenolate from alpha-SuIfonyloxy Ketone and Bis(iodozincio)methane

摘要

Treatment of alpha-sulfonyloxy ketone with bis(iodozincio)-methane gives a zinc cyclopropoxide which is formed via a nucleophilic addition of the reagent to carbonyl group followed by an intramolecular substitution reaction.Preparation of cyclopropanol has been well investigated,since Cottle reported the first example of cyclopropanol formation from epichlorohydrin in 1942.