Expression systems for the production of recombinant proteins: Mini Review

摘要

Protein expression refers to the way in which proteins are synthesized, modified and regulated in living organisms. Advances in molecular biology over the past few years have led to the cloning and expression of numerous mammalian genes in different systems. But selection of the suitable expression system depends on productivity, bioactivity, purpose and physicochemical characteristics of the protein of interest. This paper reviews the most frequently used expression systems with their merits and demerits.