Enantio-Differentiating Hydrogenation of 2-Octanone over Modified Nickel Catalysts Prepared by an In Situ Modification

摘要

The enantio-differentiating hydrogenation of 2-octanone was carried out over a tartaric acid-modified reduced nickel catalyst. It was shown that the in situ modification of the Ni surface was available for the hydrogenation of 2-octanone in the presence of a large amount of pivalic acid in the reaction media. An optical yield of 74% was attained with the in situ modified reduced Ni catalyst.