RELATIONSHIP OF NITRIC OXIDE AND PROTEIN CARBONYL IN TUBERCULOSIS

摘要

Background: Tuberculosis (TB) is a highly contagious disease caused by Mycobacterium tuberculosis. The bacilli replicate within the macrophages and can remain dormant for years; activated macrophages show immunity against these bacilli. Material and Methods: A prospective study was carried out in newly diagnosed TB patients (n=70) before their anti-tuberculosis treatment and in normal control subjects (n=35). Serum level of nitric oxide was estimated by Moshage method, 1995 and Bories and Bories method, 1995 and protein carbonyl by Levine method, 1990. Pearson's correlation (r) and Fisher's 'z' test was performed on the obtained results.