Autoimmune Polyendocrine Syndrome Presenting As Diabetic Ketoacidosis in a 20-Year-Old Woman With Crohn Disease A Case Report

摘要

Autoimmune polyendocrine syndrome (APS) is defined as a multiple endocrine gland insufficiency associated with an autoimmune disease. The first clinical manifestation of APS-1 usually occurs in childhood and new components may successively appear throughout life, with the majority of patients (63%) have 3 to 5 organ involvement. The.most frequent manifestations of APS include chronic mucocutaneous candidiasis, hypopar-athyroidism, adrenocortical failure, and gonadal failure in females. We present a case of APS that cannot be classified in any group of APS presenting with Crohn disease.