Point: Should fibrinolytics be routinely administered intrapleurally for management of a complicated parapneumonic effusion? Yes

摘要

The introduction of a therapeutic intervention into everyday clinical practice must always be given careful consideration by physicians regarding the risks and benefits the intervention poses to patients. Factors to be taken into account are the incidence of the condition being targeted, the morbidity and mortality associated with the condition, the adequacy of preexisting therapeutic approaches, the side-effect profile of the proposed intervention, and the additional financial cost incurred during the care of the patient. In this regard, one can make a strong and valid argument for the routine administration of intrapleural fibrinolytics for pleural infection (complicated parapneumonic effusion or empyema thoracis) in adults.