P-Stereogenic Phosphinates and Phosphine Oxides by Molybdenum- Catalyzed Asymmetric Ring-Closing Metathesis...

摘要

This article reports on the first examples of catalytic enantioselective olefin metathesis reactions of phosphinates and phosphine oxides, which lead to the formation of five-, six-, and seven membered P-heterocycles in up to 98% ee. Also reported is an unprecedented case of complementary asymmetric induction in reactions promoted by a pair of chiral molybdenum-based complexes differing structurally in their achiral imido ligand.