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Sublobar versus lobar resection for stage I non-small cell lung cancer: Alice's evidence.

机译:I期非小细胞肺癌的大叶下切除与大叶切除:爱丽丝的证据。

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To the Editor:Narsule et al reviewed the status of sublobar resection for early stage lung cancer and concluded that sublobar resection seemed to provide outcomes comparable to lobectomy. The difference in the survival after lobectomy and sublobar resection, however, has been debated even after 1 randomized trial. A meta-analysis, published in 2005, of 1 randomized trial and 13 nonrandomized studies indicated that survival after sublobar resection for stage I lung cancer was comparable to that after lobectomy. Herein, we would like to perform a meta-analysis of sublobar resection versus lobectomy for prevention of all-cause mortality in stage I non-small cell lung cancer (NSCLC), combining not unadjusted (as combined in the previous meta-analysis) but adjusted risk estimates in nonrandomized studies.
机译:致编者:Narsule等人回顾了早期肺癌的大叶切除术的现状,并得出结论,大叶切除术可提供与肺叶切除术相当的结果。然而,即使在一项随机试验之后,肺叶切除术和大叶下切除术后生存率的差异仍存在争议。 2005年发表的一项荟萃​​分析对1项随机试验和13项非随机研究表明,I期肺癌的大叶切除术后生存率与肺叶切除术后生存率相当。在此,我们想进行叶下切除与肺叶切除的荟萃分析,以预防I期非小细胞肺癌(NSCLC)的全因死亡率,但并非未经调整(如先前的荟萃分析所述)在非随机研究中调整风险估算值。

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