Heck reactions using water-soluble metal complexes in supercritical carbon dioxide

摘要

Heck vinylation reaction was studied using Pd(OAc)(2)/TPPTS catalyst system in supercritical carbon dioxide. The addition of co-solvents such as water and ethylene glycol significantly enhances the rate of reaction without leaching of Pd into the product phase. The reactants/products can be easily separated from the catalyst by simple phase separation and the catalyst can be recycled. (C) 1999 Elsevier Science Ltd. All rights reserved. [References: 23]