Reinvestigation relative to the regioselectivity of the aryne cycloaddition.Synthesis of the tricyclo[6.2.0.0~(2,5)]-1,5,7-triene-3,10-dione

摘要

A rapid and total synthesis of a tricyclo[6.2.0.0]deca-1,5,7-triene-3,10-dione 7b is described.Its synthesis involves the [2+2] cycloaddition of a benzyne to 2-methylene-1,3-dioxepane followed by hydrolysis to the corresponding ketone.