PREPARATION OF N-2-PROTECTED AMINO ACID ALDEHYDES VIA REDUCTION OF CORRESPONDING ACID HALIDES WITH LITHIUM TRIS-(TERT BUTOXY)-ALUMINIUM HYDRIDE

摘要

N-2-FMOC amino aldehydes, N-2-BOC amino aldehydes and N-2-Z amino aldehydes are readily preparable from N-2-FMOC amino acid chlorides and N-2-BOC and N-2-Z amino acid fluorides respectively, by reduction with lithium tris-(tert.butoxy)-aluminium hydride. [References: 11]