CO_2(CO)_8-Assisted synthesis of propargylic unsymmetrical ethers by reaction of alcohols with propargylic alcohols

摘要

Lewis acid treatment of alcohols with CO_@(CO)_6-propargylic alcohols yielded propargyulic ethers after cobalt demetallation.The procedure is highly effective for the preparation of symmetrical and unsymmetrical ethers derived from primary alcohols and primary and secondary propargylic alcohols.The method permits the use of a wide range of alcohols including those having halogens in their structures.