Use of 2-ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinoline as a convenient reagent for the selective protection or derivatization of 2-hydroxycarboxylic acids

摘要

EEDQ has been utilized as a convenient reagent for the selective protection of the hydroxy group of 2-hydroxycarboxylic acids. In the presence of an appropriate amine nucleophile, EEDQ has also been utilized as a reagent for the derivatization of both of the hydroxy and carboxylic acid group of 2-hydroxycarboxylic acids. (C) 1999 Elsevier science Ltd. All rights reserved. [References: 12]