Sequenced reactions with samarium(II) iodide, intermolecular ketyl-olefin coupling/intramolecular nucleophilic acyl substitution for the preparation of six-, seven-, and eight-membered carbocycles.

摘要

A samarium(II) iodide-promoted sequence consisting of an intermolecular ketyl-olefin coupling followed by an intramolecular nucleophilic acyl substitution is described. This process leads to functionalized six- to eight-membered monocyclic and bicyclic ring systems in moderate to good yields. (C) 1998 Elsevier Science Ltd. All rights reserved. [References: 29]