A new approach to the synthesis of functionalized 1-alkenyl-1H-1,2,3-triazoles.

摘要

The Homer-Wadsworth-Emmons (HWE) olefination of 1-[(diethoxyphosphoryl)methyl]-4,5-bis(methoxycarbonyl)-1H-1,2,3-triazole and 1-[(diethoxyphosphoryl)methyl]-5-phenyl-1H-1,2,3-triazole by means of aldehydes was found to be a convenient method for the preparation of functionalized 1-alkenyl-1H-1,2,3-triazoles in moderate to good yields and low Z/E stereoselectivity. (C) 1998 Elsevier Science Ltd. All rights reserved. [References: 28]