Novel antifeeding limonoids from Dysoxylum hainanense

摘要

Seven novel limonoids were isolated from the bark of Dysoxylum hainanense Merr, of which four were limonoid acids {dysoxylumic acids A (1), B (2), C (3), D (5)}, and three others {dysoxylumolides A (4), B (6), C (7)}. Their structures were established by extensive NMR experiments. In compounds (1)-(6), C-16 was an oxymethine group, which is rare in limonoids. Dysoxylumic acids A-C as well as known compounds dysoxylumins A-C exhibited significant antifeeding activity against Pieris rapae L, while dysoxylumolides A-C and dysoxylumic acid D showed moderate activity. (C) 2002 Elsevier Science Ltd. All rights reserved. [References: 23]