A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy, Safety, and Tolerability of Prucalopride in Men With Chronic Constipation

Yiannakou Yan; Piessevaux Hubert; Bouchoucha Michel; Schiefke Ingolf; Filip Rafal; Gabalec Libor; Dina Ion; Stephenson David; Kerstens Rene; Etherson Kevin; Levine Amy

首页> 外文期刊>The American Journal of Gastroenterology >A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy, Safety, and Tolerability of Prucalopride in Men With Chronic Constipation

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A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy, Safety, and Tolerability of Prucalopride in Men With Chronic Constipation

机译：一项随机，双盲，安慰剂对照的3期临床试验，以评估普鲁卡必利对慢性便秘患者的疗效，安全性和耐受性

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OBJECTIVES: Prucalopride is effective at alleviating symptoms of chronic constipation in women. The aim of this study was to assess the efficacy of 12 weeks of prucalopride treatment compared with placebo in men with chronic constipation.

机译：目的：普卡洛必利可有效缓解女性慢性便秘的症状。这项研究的目的是评估普卡洛必利治疗12周与安慰剂相比在慢性便秘男性中的疗效。

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《The American Journal of Gastroenterology》 |2015年第5期|共8页
作者
Yiannakou Yan; Piessevaux Hubert; Bouchoucha Michel; Schiefke Ingolf; Filip Rafal; Gabalec Libor; Dina Ion; Stephenson David; Kerstens Rene; Etherson Kevin; Levine Amy;
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正文语种 eng
中图分类消化系及腹部疾病;
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1. A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy, Safety, and Tolerability of Prucalopride in Men With Chronic Constipation [J] . Yiannakou Yan, Piessevaux Hubert, Bouchoucha Michel, The American Journal of Gastroenterology . 2015,第5期

机译：一项随机，双盲，安慰剂对照的3期临床试验，以评估普鲁卡必利对慢性便秘患者的疗效，安全性和耐受性
2. A randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of long-term treatment with prucalopride [J] . Piessevaux H., Corazziari E., Rey E., Neurogastroenterology and motility . 2015,第6期

机译：一项随机，双盲，安慰剂对照试验，用于评估长期使用普考氯普利治疗的有效性，安全性和耐受性
3. A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation [J] . WebsterL., DharS., EldonM., Pain. . 2013,第9期

机译：第2期，双盲，随机，安慰剂对照，剂量递增研究旨在评估纳洛西酚对阿片类药物致便秘患者的疗效，安全性和耐受性
4. A DOUBLE-BLIND RANDOMIZED PLACEBO-CONTROLLED CLINICAL TRIAL TO INVESTIGATE THE EFFICACY OF TIAMULIN IN THE CONTROL OF PORCINE PROLIFERATIVE ENTEROPATHY (PPE) AND PORCINE COLONIC SPIROCHAETOSIS (PCS) UNDER FIELD CONDITIONS [C] . J. Haugegaard, K. Moller, T.K. Jensen, Congress of the International Pig Veterinary Society . 2000

机译：一种双盲随机安慰剂对照临床试验，探讨硫霉素在野生植物中猪增殖肠病（PPE）和猪结肠螺旋肌肤症（PCS）的疗效
5. Effect of whey protein quality on physiological response to chronic resistance exercise in trained men: A double-blind, placebo-controlled, randomized trial. [D] . Lockwood, Christopher M. 2010

机译：乳清蛋白质量对训练有素的男性对慢性抵抗运动的生理反应的影响：一项双盲，安慰剂对照，随机试验。
6. A Randomized Double-Blind Placebo-Controlled Phase 3 Trial to Evaluate the Efficacy Safety and Tolerability of Prucalopride in Men With Chronic Constipation [O] . Yan Yiannakou, Hubert Piessevaux, Michel Bouchoucha, -1

机译：一项随机双盲安慰剂对照的3期临床试验用于评估普鲁卡必利对慢性便秘患者的疗效安全性和耐受性
7. A randomized, double-blind, placebo-controlled, phase 3 trial to evaluate the efficacy, safety, and tolerability of prucalopride in men with chronic constipation [O] . Yiannakou, Yan, Piessevaux, Hubert, Bouchoucha, Michel, 2015

机译：一项随机，双盲，安慰剂对照的3期临床试验，评估普卡洛必利在慢性便秘患者中的疗效，安全性和耐受性

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy, Safety, and Tolerability of Prucalopride in Men With Chronic Constipation

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