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首页> 外文期刊>The American Journal of Forensic Medicine and Pathology: official publication of the National Association of Medical Examiners >Genetic diversity at 15 fluorescent-labeled short tandem repeat Loci in the patel and other communities of gujarat, India.
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Genetic diversity at 15 fluorescent-labeled short tandem repeat Loci in the patel and other communities of gujarat, India.

机译:印度古吉拉特邦和其他社区的15个荧光标记的短串联重复序列基因座的遗传多样性。

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摘要

Thirteen tetranucleotide and 2 pentanucleotide repeat units were analyzed in 120 unrelated individuals of Patel and other communities of Gujarat, India. Allele frequency data obtained from the analysis of 15 short tandem repeat markers of the population were found to be satisfying Hardy-Weinberg equilibrium, with marginal deviations. Departures from Hardy-Weinberg equilibrium were observed in Patel communities at locus vWA and for that of the other communities at locus D7S820 and at locus TPOX. The power of discrimination values on an average fall within the range of 0.718 and 0.870, with deviations at locus D3S1358 showing a value of 0.400 for Patels. The value ranged between 0.709 and 0.869, with slight variations among the studied alleles in the other group. Thus, the 15 markers selected for this study were found to be highly suitable in human identification and for providing information on genetic polymorphism of the population of Gujarat.
机译:在印度Patel和印度古吉拉特邦其他社区的120位无关亲戚中,分析了13个四核苷酸和2个五核苷酸重复单元。发现通过分析种群的15个短串联重复标记而获得的等位基因频率数据满足Hardy-Weinberg平衡,且具有边际偏差。在vWA位点的Patel社区以及D7S820位点和TPOX位点的其他社区中,观察到了Hardy-Weinberg平衡的偏离。辨别力的平均值在0.718到0.870的范围内,轨迹D3S1358的偏差显示Patels的值为0.400。该值介于0.709和0.869之间,另一组研究的等位基因之间略有差异。因此,发现为这项研究选择的15个标记非常适合人类识别,并提供有关古吉拉特邦人群遗传多态性的信息。

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