New pincer-like receptor derived from trans-cyclopentane-1,2-diamine as a chiral shift reagent for carboxylic acids

摘要

A new pincer-like enantiopure receptor bearing two (1R,2R)-cyclopentane-1,2-diamine moieties has been synthesized and tested as a chiral shift reagent (CSR) for different carboxylic acids. This CSR is efficient for those acids bearing an aromatic group attached to Cot, especially for arylpropionic acids. A full structural study of the diastereomeric supramolecular complexes has allowed us to propose a reasonable model for the interaction. (c) 2007 Elsevier Ltd. All rights reserved.