Enantioselective catalysis. Part 119: New chiral 2-(2-pyridinyl)oxazoline ligands containing an additional optically active substituent in the pyridine system

摘要

The synthesis of novel chiral nitrogen ligands and their precursors is described. They consist of an optically active oxazoline bound to pyridine in the 2-position. In addition, another optically active substituent is attached to the pyridine ring. The effect of the two independent stereogenic units in one ligand was studied in the Rh(I)-catalysed enantioselective hydrosilylation of acetophenone with diphenylsilane. (C) 1998 Elsevier Science Ltd. All rights reserved. [References: 32]