The conjugate addition of enantiomerically pure lithium amides as homochiral ammonia equivalents: scope, limitations and synthetic applications

摘要

This review delineates the scope and limitations of the conjugate addition of homochiral lithium amides to act as homochiral ammonia equivalents for the asymmetric synthesis of a range of beta-amino carboxylic acid derivatives and its widespread applications in synthesis. (c) 2005 Elsevier Ltd. All rights reserved.