Determination of the absolute configuration of fasidotril, a potent dual ACE/NEP inhibitor

Grosset V.; Danvy D.; Capet M.

首页> 外文期刊>Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry >Determination of the absolute configuration of fasidotril, a potent dual ACE/NEP inhibitor

【24h】

Determination of the absolute configuration of fasidotril, a potent dual ACE/NEP inhibitor

机译：法西多利（一种有效的双重ACE / NEP抑制剂）的绝对构型测定

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The absolute configuration of fasidotril has been established by a chemical correlation leading to the stereochemical assignment of the intermediate (S)-3-acetylsulfanyl-2-(benzo[1,3]dioxol-5-ylmethyl)propanoic acid. (C) 2003 Elsevier Ltd. All rights reserved. [References: 12]

著录项

来源
《Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry》 |2003年第16期|共3页
作者
Grosset V.; Danvy D.; Capet M.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类有机化学;
关键词
Hypertension;

机译：高血压;

相似文献

外文文献
中文文献
专利

1. Determination of the absolute configuration of fasidotril, a potent dual ACE/NEP inhibitor [J] . Grosset V., Danvy D., Capet M. Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry . 2003,第16期

机译：法西多利（一种有效的双重ACE / NEP抑制剂）的绝对构型测定
2. Efficient asymmetric syntheses, determination of absolute configurations and biological activities of l-[4,4-bis(4-fluorophenyl)butyl]-4-[2-hydroxy-3-(phenylamino)propyl]-piperazine as a novel potent dopamine uptake inhibitor in the central nervous syste [J] . Makoto Kimura, Tomoko Masuad, Koji Yamada, Bioorganic and medicinal chemistry . 2004,第11期

机译：有效的不对称合成，确定的绝对构型和生物学活性的l- [4,4-双（4-氟苯基）丁基] -4- [2-羟基-3-（苯基氨基）丙基]哌嗪作为一种有效的多巴胺摄取中枢神经系统抑制剂
3. Efficient asymmetric syntheses, determination of absolute configurations and biological activities of l-[4,4-bis(4-fluorophenyl)butyl]-4-[2-hydroxy-3-(phenylamino)propyl]-piperazine as a novel potent dopamine uptake inhibitor in the central nervous syste [J] . Makoto Kimura, Tomoko Masuad, Koji Yamada, Bioorganic and Medicinal Chemistry . 2004,第11期

机译：有效的不对称合成，确定的绝对构型和生物学活性的l- [4,4-双（4-氟苯基）丁基] -4- [2-羟基-3-（苯基氨基）丙基]哌嗪作为一种有效的多巴胺摄取中枢神经系统抑制剂
4. Synthesis of the first highly potent inhibitor of the three vasopeptidases:endothelin converting enzyme (ECE),angiotensin converting enzyme (ACE) and neprilysin (NEP) [C] . Nicolas Inguimbert, Herve Poras, Pascale Coric, European Peptide Symposium . 2002

机译：三种血管肽酶的第一高效抑制剂的合成：内皮素转化酶（ECE），血管紧张素转化酶（ACE）和Neplysin（NEP）
5. Determination of the Absolute Configuration of β-Chiral Primary Alcohols Using the Competing Enantioselective Conversion Method Heteroatom-directed Acylation of Secondary Alcohols to Assign Absolute Configuration Total Synthesis of Illisimonin a Osmate Es [D] . Burns, Alexander Sunshine. 2020

机译：使用竞争对映选择性转化法测定β-chiral初级醇的绝对构型次原子为仲醇的酰化酰化，分配绝对构型Illisimonin的总合成渗透
6. Discovery of a Pair of Diastereomers as Potent HDACs Inhibitors: Determination of Absolute Configuration Biological Activity Comparison and Computational Study [O] . Yingjie Zhang, Elizabeth S. Inks, Mengyuan Zhu, -1

机译：发现一对非对映体作为强效HDAC抑制剂：绝对构型的确定生物活性比较和计算研究
7. Fasidotril: The First Dual Inhibitor of Neprilysin and ACE [O] . J. Bralet, C. Marie, C. Gros, 2006

机译：fasidotril：Neplysin和Ace的第一个双重抑制剂

Determination of the absolute configuration of fasidotril, a potent dual ACE/NEP inhibitor

摘要

著录项

相似文献

相关主题

期刊订阅