A new simple preparation of D-alloisoleucine suitable for large-scale manufacture

摘要

D-Alloisoleucine (D-aIle) was obtained by the resolution of the epimer mixture Of L-isoleucine (L-Ile) and D-alle, which was formed by epimerization Of L-Ile, with a resolving agent such as (2S, 3S)-dibenzoyltartaric acid ((2S,3S)-DBTA) or (2S,3S)-di-4-toluoyl tartaric acid ((2S,3S)-DTTA). (C) 2002 Elsevier Science Ltd. All rights reserved. [References: 18]