Studies on stereocontrolled epoxidations of bis-alicyclic alcohols in steroidal skeletons: preparation of eight diastereomerically pure epoxides from cholest-4-en-3 beta,6 beta-; -3 beta,6 alpha-; -3 alpha,6 beta- and -3 alpha,6 alpha-diols

摘要

Eight diastereomerically pure epoxides have been prepared from cholest-4-en-3 beta .6 beta: -3 beta .6 alpha-: -3 alpha .6 beta- and -3 alpha .6 alpha -diols via a combination of steric, protecting group and oxidant effects on stereocontrolled epoxidations of a bis-alicyclic alcohol system within the steroidal skeleton. (C) 2001 Elsevier Science Ltd. All rights reserved. [References: 25]