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首页> 外文期刊>Pathology Research and Practice >Melanocytoma of ciliary body and choroids simulating melanoma.
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Melanocytoma of ciliary body and choroids simulating melanoma.

机译:睫状体的黑素细胞瘤和模拟黑色素瘤的脉络膜。

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摘要

Melanocytoma is a rare intraocular tumor. There are some reports in the literature dealing with primary melanocytomas of the choroid and ciliary body. It is believed that most of these tumors are clinically diagnosed as nevi or melanoma, and are followed up or treated without surgical resection, respectively. Some clinical features can give a clue as to the correct diagnosis. We report on a 47-year-old white female with progressive visual loss of 2 months and right painful eye. Her visual acuity of finger counting was confined to 3.0m OD and 20/20 OS. Biomicroscopy OD showed a 360 degrees posterior synechia, and fundoscopy was not conclusive due to vitreous opacity. No alterations were seen on OS. Intraocular pressure was normal, and the pupillary reflex was present in both eyes. An ultrasound of the OD showed an elevated tumor on topography of the ciliary body and anterior choroid at the ora serrata level. Melanoma was the main diagnosis considered, and enucleation was indicated due to poor prognosis for visual acuity. Gross and histopathologic examinations of the OD showed a heavily pigmented tumor. The brownish pigment obscured the morphology of the tumor cells that could not be visualized by conventional H&E stain. Bleached slides showed that tumor was composed of melanocytoma cells type I.
机译:黑素细胞瘤是一种罕见的眼内肿瘤。文献中有一些有关脉络膜和睫状体原发性黑素细胞瘤的报道。据信,这些肿瘤中的大多数在临床上被诊断为痣或黑色素瘤,并且无需手术切除就可以进行随访或治疗。一些临床特征可以为正确诊断提供线索。我们报告了一位47岁的白人女性,其进行性视力丧失为2个月,右眼疼痛。她的手指计数视力仅限于OD为3.0m和OS为20/20。生物显微术OD显示360度后粘连,由于玻璃体混浊,眼底镜检查尚无定论。在OS上未见任何更改。眼内压正常,两只眼睛均出现瞳孔反射。 OD的超声显示在口锯缘水平的睫状体和前脉络膜的地形上肿瘤升高。黑色素瘤是考虑的主要诊断方法,由于视力预后不良,因此建议行摘除术。 OD的大体和组织病理学检查显示有大量色素沉着的肿瘤。褐色颜料遮盖了常规H&E染色无法观察到的肿瘤细胞形态。漂白片显示肿瘤由I型黑素细胞瘤细胞组成。

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