Gelatinous transformation of the bone marrow as a late morphological change in imatinib mesylate treated chronic myeloid leukaemia.

摘要

Gelatinous transformation of the bone marrow is a well recognised pathological manifestation in people with cachex-ia consequent to malignancy, chronic infections or anorexia nervosa.1 However, with the advent of imatinib for the treatment of chronic myeloid leukaemia, there appears to be an emerging new cause for this manifestation.A 44-year-old male nurse was referred to the Haematology Department with characteristic peripheral blood, bone marrow and cytogenetic features of chronic myeloid leukaemia (CML) in chronic phase. He was completely asymptomatic at diagnosis.