Dominant nodule and papillary thyroid carcinoma in hashimoto thyroiditis: clinicopathologic correlations in a series of 266 patients

摘要

Background. Some patients affected by Hashimoto thyroiditis (HT) may develop one or more nodules (> 1 cm), so-called "dominant nodule" (DN). Due to the association between HT and papillary thyroid carcinoma (PTC), the detection of DNs is alarming, with the indication to perform FNAC. Accordingly the aim of the present study was to investigate: i) the clinicopathological features of DN in HT; ii) the predictive value of DN for a concurrent PTC elsewhere in the thyroid gland.