A Prospective Randomized Trial Comparing Silver Sulfadiazine Cream With a Water-Soluble Polyantimicrobial Gel in Partial-Thickness Burn Wounds

摘要

According to the American Burn Association, 450,000 patients sought medical care for burns in 2012, with a 96.1% survival rate (American Burn Association, 2012). This represents a dramatic improvement from the mortality rates seen before early burn wound excision and grafting was introduced 0anzekovic, 1970). Nevertheless, topical antimicrobials remain a cornerstone in the care of the burn patient. The ideal antimicrobial therapy will provide broad coverage, allow an environment for wound assessment, allow for rapid wound healing, and minimize the utilization of resources. Minimizing pain, dressing care complexity, and personnel resources to deliver care are important to treatment success and cost control. Multiple options exist, but none has been proven superior (Wasiak, Cleland, & Campbell, 2008).