Efficacy of Sodium Hypochlorite in Eradicating Hepatitis C Virus (HCV)-RNA from the Peritoneal Effluent of PD Patients.

摘要

Hepatitis C virus (HCV) constitutes an important health problem among the population with chronic renal failure: in 15% - 20% according to various studies (1-8). Although different routes of transmission have been described, in an important number of patients the source of infection remains unknown. Peritoneal dialysis (PD) has been suggested as a better option than hemodialy-sis for dialysis in patients with HCV. Nevertheless, some 2% - 5% of patients treated with PD demonstrate serum antibodies against HCV. Although it is possible to find HCV in corporal fluids, even ascites (9), there are very few studies in PD patients on the risk of dissemination of HCV-RNA through the peritoneal effluent (10-15), and the conclusions of the aforementioned studies are contradictory. There are no published data on the eradication of HVC-RNA from the peritoneal effluent.