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Robotic partial adrenalectomy using indocyanine green dye with near-infrared imaging: The initial clinical experience

机译:使用吲哚菁绿染料进行近红外成像的机器人部分肾上腺切除术:初始临床经验

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摘要

Objective: To present the initial clinical experience with robot-assisted partial adrenalectomy using indocyanine green dye with near-infrared fluorescence (ICG-NIRF) imaging. Methods: Three consecutive patients with solitary adrenal masses with worrisome features were referred for treatment. The preoperative workup included dedicated axial imaging and adrenal function studies. All patients underwent purely robotic partial adrenalectomy with ICG-NIRF guidance. Relevant steps of the technique included a transperitoneal approach, gross identification of the adrenal gland, administration of 5 mg intravenous ICG, and finally, mass resection guided by ICG-NIRF and white light visualization in an effort to completely excise the mass while sparing uninvolved adrenal tissue. Results: Robotic partial adrenalectomy was successfully performed with negative margins in all patients. All masses were hypofluorescent relative to normal adrenal tissue with ICG-NIRF and included a pheochromocytoma, lipoadenoma, and follicular lymphoid hyperplasia. Conclusion: Robotic partial adrenalectomy with intraoperative ICG-NIRF is safe and feasible. The addition of ICG-NIRF may help mass identification, excision, and promote the use adrenal-sparing surgery.
机译:目的:介绍使用吲哚菁绿染料进行近红外荧光(ICG-NIRF)成像的机器人辅助部分肾上腺切除术的初步临床经验。方法:连续三例患有令人担忧的特征的孤立性肾上腺肿块的患者被转诊。术前检查包括专门的轴向成像和肾上腺功能研究。所有患者均在ICG-NIRF指导下接受纯机器人部分肾上腺切除术。该技术的相关步骤包括经腹膜入路,大致识别肾上腺,给予5 mg静脉ICG,最后在ICG-NIRF和白光可视化的指导下进行肿块切除,以在不累及肾上腺的同时完全切除肿块组织。结果:所有患者均成功进行了机器人局部肾上腺切除术,切缘阴性。相对于具有ICG-NIRF的正常肾上腺组织,所有肿块均为低荧光性,包括嗜铬细胞瘤,脂肪腺瘤和滤泡性淋巴增生。结论:术中ICG-NIRF机器人局部肾上腺切除术安全可行。加入ICG-NIRF可能有助于大量鉴别,切除并促进使用保留肾上腺的手术。

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