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Do silver alloy-coated catheters increase risk of urethral strictures after robotic-assisted laparoscopic radical prostatectomy?

机译:机器人辅助腹腔镜前列腺癌根治术后,涂银合金的导管是否会增加尿道狭窄的风险?

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OBJECTIVES: To evaluate whether the use of silver-coated catheters increased the risk of developing urethral stricture disease after robotic-assisted laparoscopic radical prostatectomy (RALP). Recently, silver alloy-coated Foley catheters have been shown to decrease the risk of catheter-associated urinary tract infections. Other than the increased cost, no disadvantages to the use of these catheters have been reported. MATERIAL AND METHODS: We switched to routine use of the Bardex I.C. silver alloy-coated Foley catheters for all urologic procedures on November 1, 2008. After institutional review board approval, we retrospectively reviewed the records of all consecutive patients who had undergone RALP 12 months before and after the catheter change. The primary outcome was the rate of urethral strictures after RALP. RESULTS: A total of 188 RALPs were performed during the 12 months before the catheter change. No patients who underwent RALP in the months before the catheter change had developed a new postoperative urethral stricture. In the 12 months after the change to the silver-coated catheters, 217 RALPs were performed. Six patients after RALP using silver-coated catheters developed new strictures, at a rate of 2.8% (P = .03). CONCLUSIONS: Silver alloy-coated urinary catheters might increase the risk of developing urethral strictures after RALP compared with standard noncoated catheters. Additional evaluation by a large randomized prospective trial is warranted to elucidate the true risk of stricture formation.
机译:目的:评估在机器人辅助的腹腔镜前列腺癌根治术(RALP)后使用镀银导管是否会增加发生尿道狭窄疾病的风险。最近,银合金涂层的Foley导管已被证明可以降低与导管相关的尿路感染的风险。除了增加的成本外,没有报告使用这些导管的缺点。材料和方法:我们改用Bardex I.C.的常规用法。于2008年11月1日对所有泌尿科手术进行涂有银合金涂层的Foley导管。在获得机构审查委员会的批准后,我们​​回顾性地回顾了在更换导管前后12个月内接受RALP的所有连续患者的记录。主要结局是RALP后尿道狭窄的发生率。结果:在更换导管前的12个月中共进行了188次RALP。在更换导管前的几个月中没有接受过RALP的患者没有出现新的术后尿道狭窄。更换为镀银导管后的12个月内,进行了217次RALP。 RALP后有6例患者使用了涂银导管,出现了新的狭窄,比率为2.8%(P = .03)。结论:与标准的无涂层导尿管相比,涂有银合金的导尿管可能增加RALP后发生尿道狭窄的风险。有必要通过一项大型的随机前瞻性试验进行额外评估,以阐明形成狭窄的真正风险。

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