Limbic encephalitis is characterized by the subacute progression of short-term memory loss, disorienta-tion, confusion, and agitation.1'2 Hallucinations, behavioral and personality changes, temporolimbic seizures, sleep disturbances, and dysautonomia may also occur. The pyramidal layer of the hippocampus and the amygdaloid nuclei are particularly susceptible and demonstrate neuronal loss, reactive gliosis, and perivascular lympho-cytic cuffing.1 Magnetic resonance imaging (MRI) typically reveals increased signal in limbic structures on T2, fluid-attenuated inversion recovery (FLAIR), and diffusion-weighted imaging (DWI).
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