Arginine vasopressin 1a receptor RS3 promoter microsatellites in schizophrenia: A study of the effect of the 'risk' allele on clinical symptoms and facial affect recognition

摘要

We studied AVPR1A RS3 polymorphism in schizophrenic patients and controls. AVPR1A RS3 was not associated with schizophrenia. The allele 327bp implicated in autism and social behavior was associated with negative symptoms and tended to be linked to patient facial affect recognition suggesting its impact on schizophrenia social phenotypes. (C) 2014 Elsevier Ireland Ltd. All rights reserved.