Moving liquids with sound helps identify drug candidates that traditional lab techniques miss

摘要

How do researchers know whether new molecules will have a positive or negative effect? How much does the technique for moving a liquid affect the results? What about testing compounds for their environmental or health impacts: is one liquid handling process better than another when it comes to accuracy of the data? A paper published by the journal PLOS ONE, May 1, 2013, demonstrates that the technique used to transfer compound solutions does indeed matter. The three researchers who wrote "Dispensing Processes Impact Apparent Biological Activity as Determined by Computational and Statistical Analyses", (http://dx.plos.org/l0.1371 /journal.pone.0062325) conclude that if traditional techniques introduce errors early in the scientific process, the implications are vast.