Mastering ozonolysis: production from laboratory to ton scale in continuous flow

摘要

in most cases, ozonolysis is more sustainable and cost effective for the oxidative treatment of organic unsaturated compounds than other oxidation technologies. To enable the scalability of this challenging gas-liquid oxidation process, Lonza has developed a novel approach that combines microreactors, a bench-scale reactor, and a large scale production reactor. The approach also includes laboratory feasibility studies and technical transfer - with hazard evaluations and safety assessments - to successful large scale manufacturing.