The Trifluoromethylgroup An overview of available synthetic methods at Solvias AG

摘要

This overview highlights some available methods for the introduction of a CF3-group into a molecule on laboratory and industrial scale. Thus, methods relying on transfer reagents for the nucleophilic and electrophilic trifiuormethylation are being discussed, while also industrial applicable efficient methods focusing on functional group inter-conversion are being highlighted.