2,2,6,6-Tetraalkylpiperidine-N-oxyls and N-alkoxyamines (part I) Nitroxide radicals in organic synthesis

摘要

This review aims at demonstrating the enormous scope of 2,2,6,6-tetraalkylpiperidine N-O compounds (nitroxide radicals and N-aikoxyamines) both in academia and in industrial applications. Beyond classical TEMPO-catalysed oxidation reactions, these substances may for instance be applied as carbon radical scavengers, polymerisation initiators, spin labels, in materials science, biological processes, protein analytics, or for the stabilisation of polymers. In a first part, recent applications of N-oxyl compounds (mainly TEMPO and its derivatives) in synthetic organic chemistry will be presented. In a subsequent part (next issue), the reader will be familiarised with the use of nitroxide radicals and the closely-related N-alkoxyamines in an industrial context as well as in intriguing and upcoming academic fields.