Synthesis, Characterization, and Antioxidative Activity of Ternary Rare-Earth Complexes of 5-Fluorouracil-l-acetic Acid and 2,2'-Bipyridine

摘要

Seven new solid ternary complexes of 5-fluorouracil-l-acetic acid (HFAA) and 2,2'-bipyridine (Bipy) with rare-earth metals have been synthesized. Elemental analysis, molar conductivity, IR, TG-DTA, UV, and XH NMR spectra have been used to characterize these complexes. The general formula for the complexes is M(FAA)sBipy o 71H2O, where M = Y, La, Ce, Sm, Gd, Dy or Er, n = 0, 2 or 5. The antioxidative activity of these complexes was tested. The results obtained showed that the suppression ratios of these complexes for O'2~ free radical are mostly higher than those of HFAA and Bipy.